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KMID : 0370919940110010101
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Yeungnam Univercity Journal of Medicine
1994 Volume.11 No. 1 p.101 ~ p.108
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Estimation of Glomerular Filtration Rate(GFR) Using Tc DTPA Renal Scan and the Parameters for Renal Function
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조인호
윤현대/원규강/이찬우/이형우/이현우
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Abstract
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Many previously described nuclear medicine procedures to assess glomerular filtration rate have some problems because numerous blood sample is to be taken and they don't measure each separate renal function. Gates described isotopic method for
the
measurement of global and unilateral GFR based on the fractional renal uptake of 99mTc-DTPA 2 to 3 minutes after its intravenous injection.
We evaluated GFR using 99mTc-DTPA in 57 people according to Gates method and compared with creatinine clearance. A good correlation was observed between creatinine clearance and GRF calculated by Gates' formula with an r value of 0.9(P<0.05).
And also the relationship between parameters of 99mTc-DTPA renal scan images and GFR was taken. They were significantly correlated with GFR calculated by Gates' formula : r value 0.66 between relative intensity of peak renal to peak aortic
activity(pK/pA) and GFR, -0.42 between time between aortic and kidney peak(A-K) and GFR and -0.48 between parenchymal renal activity at 25 min compared to peak kidney activity(25K/pK) and GRF.
In conclusion, the determination of GFR according to Gates' formula shows good and reproducible of GRF with rapidity and simplicity. And the parameters from the renal scan images can use to estimate the renal function.
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KEYWORD
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